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ARTICLE-60: Granting of authorisations [go to this ARTICLE]
... (a) the risk posed by the uses of the substance, including the appropriateness and effectiveness of the risk management measures proposed; ...
... (a) whether the transfer to alternatives would result in reduced overall risks to human health and the environment, taking into account the appropriateness and effectiveness of risk management measures; ...
ARTICLE-64: Procedure for authorisation decisions [go to this ARTICLE]
... (a) Committee for Risk Assessment: an assessment of the risk to human health and/or the environment arising from the use(s) of the substance, including the appropriateness and effectiveness of the risk management measures as described in the application and, if relevant, an assessment of the risks arising from possible alternatives; ...